Innovation Goals

Using Systems Biology and Precision Medicine to achieve Medical Innovation

A major barrier to the early detection and diagnosis of chronic diseases, as well as selecting the most effective therapy for an individual patient, is the insufficient understanding of the disease at the cellular level. Defining when, why, and how cells deviate from healthy states in stratified patient groups, is key for developing more inclusive and precise treatments.

The NIMSB mission is to pioneer excellent interdisciplinary research aimed at detecting – with unprecedented precision – the earliest cellular changes that trigger the onset of disease. Such sensitive detection is made possible by the integration of new breakthrough technologies, including single-cell and spatial multi-omics, artificial intelligence, and patient-derived disease models, such as organoids and organs-on-a-chip.

Ultimately, NIMSB aims at translating new discoveries on early pathological causative cellular changes into novel diagnostics with increased accuracy for disease detection, thus generating unforeseen therapeutic opportunities to intercept disease before the occurrence of irreparable damage to tissues and organs.